The Tennessee Titans' season went from bad to worse.

Last year's best regular season team saw its winless campaign extended to six games with a 59-0 pummelling at the New England Patriots' snowy Gillette Stadium.

The Patriots moved to 4-2 for the season as quarterback Tom Brady threw six touchdown passes, an NFL record five in the second quarter, and completed 29 of his 34 passes for 380 yards.

Wide receivers Randy Moss and Wes Welker were the main beneficiaries, catching three and two TD passes respectively while Kevin Faulk caught one and Laurence Moroney rushed for a touchdown.

Having thrown a career-high number of touchdown passes, Brady was replaced by rookie quarterback Brian Hoyer in the third quarter and the stand-in rushed one yard for a touchdown of his own as the Patriots matched the Los Angeles Rams 59-0 win over Atlanta in 1976 as the biggest score since the NFL merged with the American Football League in 1970.

The Titans, which ended the 2008 season with a 13-3 record, are now 0-6 following their worst defeat since the team's inception as the Houston Oilers in 1960.

The all-New York state match-up between the Jets and the Bills went into overtime at the Meadowland as visiting Buffalo's kicker Rian Lindell missed a field goal four seconds from the end of regular time with the score 13-13.

Lindell made amends with 2:46 of OT left when he did convert the game-winning field goal from 47 yards out for a 16-13 victory, handing the Jets a third loss in a row.

The Jets' rookie quarterback Mark Sanchez was intercepted five times and completed only 10 of 29 passes.

Elsewhere, the Oakland Raiders notched their second win of the season with a 13-6 defeat of the Philadelphia Eagles, while in Seattle, the Seahawks lost for the fourth time in six games, beaten 27-3 by the visiting Arizona Cardinals, who move to 3-2.

In the night's late game, Michael Turner scored the go-ahead touchdown with three minutes remaining as the Atlanta Falcons defeated the Chicago Bears 21-14 at the Georgia Dome.

A fourth-quarter touchdown by tight end Greg Olsen from a short pass by quarterback Jay Cutler had put the Bears back on level terms after the Falcons had led 14-7 at the half, Atlanta's Matt Ryan throwing two touchdown passes in response to Cutler's opening salvo to Johnny Knox at the start of the second quarter.

Yet the Falcons had one more score in them and Turner's rush sealed the win to send Atlanta to a 4-1 record for the season, the Bears slipping to 3-2.